Synthesis and Bioactivity of 1-((2-carbamoylguanidino)(furan-2-ylmethyl)urea

Publication Date : 01/05/2020

Author(s) :

Don-Lawson Chioma, K. J. Orie, R. Okah.

Volume/Issue :
Volume 1
Issue 1
(05 - 2020)

Abstract :

1-((2-carbamoylguanidino)(furan-2-ylmethyl)urea was synthesised by coupling purified furfural with urea. The compound was characterized by GC-MS, FTIR,and 1H-NMR. The pathogens, Escherichia coli, Salmonella typhi, Staphylococcus aureus and Bacillus subtilis were isolated and screened with different concentrations of 1-((2-carbamoylguanidino)(furan-2-ylmethyl)urea. All the pathogens were susceptible to the synthesized compound except Bacillus subtilis. Due to this broad spectrum of activity, 1-((2-Carbamoylguanidino)(furan-2-ylmethyl)) urea) can be use for various medicinal purposes and is therefore encouraged for the development of a novel drug in future.

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